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| Analysis of abnormal status and influencing factors of fasting blood glucose among planning pregnancy women in Henan rural |
| 1.Henan Institute of Reproduction Health Science and Technology, NHC Key Laboratory of Birth Defects Prevention, Henan Key Laboratory of Population Defects Prevention, Zhengzhou，Henan Province, 450002; 2. Hua County Maternal and Child Health Care Hospital of Henan |
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Abstract To investigate the status and influencing factors of abnormal fasting blood glucose among planning pregnancy women in rural areas of Henan province. Methods: 386786 planning pregnancy women of childbearing age who had been given free pre-pregnancy eugenic health examination in 158 counties or districts of Henan province from January to December 2018 were selected and were divided into three groups, which included the women with normal fasting glucose (NGT) in group A, the women with impaired fasting glucose (IFG) in group B, and the women with diabetes mellitus (DM) in group C. The abnormal fasting glucose included IFG and DM. Multiple Logistic regression analysis was used to analyze the influencing factors of abnormal fasting glucose of the women. Results: There were 7900 (2.0%) women in group B and 4158 (1.1%) women in group C, and the rate of fasting glucose level abnormality of the women was 3.1%. The risk of IFG and DM of the women increased with age (P＜0.05). The risks of IFG (odds ratios (OR)=1.208，95%CI: 1.148-1.272) and DM (OR=1.139，95%CI: 1.062-1.221) of the women with senior high school education level or above were significantly higher than those women with junior high school education level or below. The risks of IFG and DM of the women with overweight and obesity, hypertension, thyroid stimulating hormone (TSH) abnormality, tobacco exposure, or viral hepatitis B (HBV) infection increased significantly (P＜0.05). The risks of IFG (OR=0.870, 95%CI: 0.823-0.921) and DM (OR=0.812, 95%CI: 0.750-0.878) of the women with previous pregnancy history decreased significantly. Conclusion: Advanced age, high education level, with family hstary of diabetes overweight and obesity, hypertension, abnormal TSH level, tobacco exposure, and HBV infection of the planning pregnancy women are the risk factors for their abnormal fasting blood glucose level, but the previous pregnancy history of the women is the protective factor for their abnormal fasting blood glucose level.
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