To investigate the value of radiomics-based model of half-Fourier acquisition single-shot turbo spin-echo (HASTE) and true fast imaging with steady-state precession (true-FISP) combined with free beta-human chorionic gonadotropin (β-HCG) level for predicting placenta accreta. Methods: The clinical data of 137 women with suspected placenta accreta from February 2018 to March 2021 were collected retrospectively, and these women had received examination of radiomics-based model of HASTE and true-FISP. These women were divided into group A (123 women with positive results) and group B (14 women with negative results) according to the pathological results after surgery as the gold standard. The women in the two groups were given serum β-HCG level detection. The positive rate of HASTE and true-FISP, and the serum β-HCG level of the women in the two groups were analyzed. Receiver operating characteristic (ROC) curve was used to evaluate the predictive value of radiomics-based model of HASTE and true-FISP and the β-HCG level for placenta accreta. Results: Among 137 women with suspected placenta accreta, 126 cases were confirmed by postoperative pathology, and the positive rates of placenta accreta by HASTE and true-FISP were 88.6% and 85.4%. The level of serum β-hCG of the women in group A was significantly higher than that of the women in group B (P<0.05). The sensitivity and the specificity of HASTE for predicting placenta accreta were 88.6% and 42.9%, the sensitivity and the specificity of true-FISP for predicting placenta accreta were 85.4% and 50.0%, and the sensitivity and the specificity of the β-HCG level for predicting placenta accreta were 86.2% and 64.3%. The sensitivity and the specificity of HASTE and true-FISP combined with he β-HCG level for predicting placenta accreta were 96.7% and 85.7% (P<0.05). Conclusion: Radiomics-based model of HASTE and true-FISP combined with the β-HCG level for diagnosis of the antenatal placenta accreta of the pregnant women is higher, which is worthy of application in clinic.