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Abstract To explore the effect of Maiqi jiangtang pill combined with insulin for treating pregnant women with gestational diabetes mellitus(GDM). Methods: 124 pregnant women with GDM were divided into control group and study group(62 cases in each group) according to random number table method from March 2018 to January 2019. All women were given routine intervention combined with insulin asparagus, and the women in the treatment group were given Maiqi jiangtang pill additionally. The results of oral glucose tolerance test(OGTT), the changes of blood glucose indicators levels, the levels of insulin index, the levels of serum total bilirubin(TBil), uric acid(UA), and urinary microalbumin(mAlb), and the pregnancy outcomes of the women were compared between the two groups. Results: The rate of normal 75g OGTT results(95.2%) of the women in the study group after treatment was significantly higher than that(82.3%) of the women in the control group(P<0.05). The levels of fasting blood glucose, blood glucose, and glycosylated hemoglobin of the women in the two groups in 1h and 2h after 75g OGTT had decreased significantly, and the levels of insulin resistance index, insulin secretion index, and the levels of serum TBil, UA, and urinary mAlb of the women in the two groups had increased after treatment, and which of the women in the study group were significantly better than those of the women in the control group(all P<0.05). The incidences of adverse pregnancy outcomes, such as cesarean section, premature rupture of membranes, polyhydramnios, premature birth, macrosomia, and neonatal jaundice of the women in the study group were significantly lower than those of the women in the control group(P<0.05). Conclusion: Maiqi jiangtang pill combined with insulin for treating pregnant women with GDM can significantly improve their blood glucose level and insulin function, can effectively regulate the levels of TBil, UA, and mAlb, and can significantly improve pregnancy outcomes of these women.
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