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| Effects of different doses of remifentanil for painless delivery of pregnant women on their pain and motor nerve block of lower extremity |
| Ding’an People's Hospital，Hainan Province, 571200 |
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Abstract Effects of different doses of remifentanil for painless delivery of pregnant women on their visual analogue scale (VAS) score and motor nerve block of lower extremity (Bromage) score. Methods: 152 pregnant women who wanted painless delivery were selected and were randomly divided into two groups (76 cases in each group) by random number table from October 2018 to November 2020. The women in group A were given 1.5 mg remifentanil for analgesia，and the women in group B were given 1 mg remifentanil for analgesia. The VAS score, the values of vital signs, such as blood pressure (BP), Heart rate (HR), respiratory rate (RR), the levels of cortisol (Cor), adrenaline (ADR), and interleukin-6 (IL-6), and Bromage score of the women before anesthesia, in anesthesia 30min, and in anesthesia 6h, and the Apgar score of the newborn were observed. The incidence of adverse reactions was calculated. Results: VAS scores of the women in both groups had decreased significantly in anesthesia 30min, but which had increased significantly in anesthesia 6h. The values of BP, HR, and RR of the women in both groups had decreased in anesthesia 30min and 6h significantly, and the levels of Cor, ADR, and IL-6 of the women in both groups had increased significantly in anesthesia 30min and 6h. The VAS score and the values of BP, HR, and RR of the women in both groups in anesthesia 6h were significantly higher than those in anesthesia 30min, while the Cor, ADR and IL-6 levels of the women in both groups in anesthesia 6h were significantly lower. The Cor, ADR and IL-6 levels of the women in group B in 30min and 6h of anesthesia were significantly lower than those of the women in group A.VAS score of the women in group B in 30min and 6h of anesthesia(1.67±0.68 points and 89±0.36 points)were significantlyhigher than those (1.04±0.85 points and 3.27±0.23 points) of the women in group A. The total incidence of adverse reactions (4.0%) of the women in group B was significantly lower than that (13.2%) of the women in group A, and the values of BP, HR, and RR of the women in group B were significantly higher than those of the women in group A. The Bromage score (0.84±0.36 points) of the women in group B after delivery successfully was significantly lower than that (1.13±0.47 points) of the women in group A. Apgar score (9.57±0.38 points) of the newborn in group B was significantly higher than that (8.81±0.26 points) of the newborn in group A (all P<0.05). Conclusion: 1mg remifentanil for painless delivery of the pregnant women can improve their VAS score, reduce their Bromage score and incidence of adverse reactions, and improve Apgar score of their newborn.
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