To explore the levels of serum neutrophil gelatinase-related lipid carrying protein (NGAL), anti-mullerian tubular hormone (AMH), and inhibin B (INHB) of pregnant women with polycystic ovary syndrome (PCOS), and to study their correlation with the adverse pregnancy of the women. Methods: 93 pregnant women with PCOS were included in study group and 50 healthy pregnant women were included in control group from August 2019 to August 2021. The levels of serum AMH, INHB, and NGAL of the women in the two groups were detected, and the correlation between which and the adverse pregnancy of the women was analyzed by multiple linear regression. Results: The incidence of adverse pregnancy (63.4%), and the levels of serum NGAL (100.26±5.26mmol/L), AMH (9.16±3.02ng/ml), and INHB (146.22±12.23ng/ml) of the women in the study group were significantly higher than those (22.0%, 41.22±2.01mmol/L, 5.46±0.22ng/ml, and 100.23±7.06ng/ ml) of the women in the control group, and which of the women with normal pregnancy outcomes serum level were significantly higher than those of the women with adverse pregnancy outcomes (all P<0.05). Regression analysis showed that the levels of serum NGAL, AMH, and INHB of the pregnant women with PCOS were correlated with their adverse pregnancy (P<0.05). Conclusion: The serum NGAL, AMH, INHB expression of the pregnant women with PCOS increase abnormally, and which are correlated with their adverse pregnancy.