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Study of the expression levels and the correlation of serum vitamin E and D, and total bilirubin and indirect bilirubin of pregnant women with pregnancy induced hypertension |
Xuancheng Central Hospital, Anhui Province, 242000 |
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Abstract To explore the expression levels and the correlation of serum vitamin E and D, and total bilirubin and indirect bilirubin of pregnant women with pregnancy induced hypertension (PIH). Methods: 40 pregnant women with PIH gestational hypertension were selected in study group, and 50 normal pregnant women undergoing physical examination were selected in control group from May 2017 to May 2018. The expression levels of serum vitamin E and D, and total bilirubin and indirect bilirubin of the women in the two groups were detected, and the correlation between which of the women and the PIH was analyzed. Results: The levels of vitamin E (23.46±1.97 ng/ml), vitamin D (9.42±1.98 ng/ml) and the total bilirubin (94.00±9.31 mg/L) of the women in the study group were significantly lower than those (29.21±3.45 ng/ml, 20.42±7.10 ng/mL, and 15.20±11.39 mg/L) of the women in the control group, but the indirect bilirubin level (3.97±1.02μmol/L) of the women in the study group was significantly higher than that (3.06±0.72μmol/L) of the women in the control group (all P<0.05). In the study group, there were significant differences in the levels of serum vitamin E and D, and total bilirubin and indirect bilirubin levels among the women with different family history, with different urinary protein level, and with different value of body mass index before pregnancy (P<0.05). The vitamin E level of the women with PIH was positively correlated with their vitamin D and indirect bilirubin levels, and which was negatively correlated with their total bilirubin level. The Vitamin D level of the women with PIH was positively correlated with their total bilirubin level, and which was negatively correlated with their indirect bilirubin level. The total bilirubin level of the women with PIH was negatively correlated with their indirect bilirubin level (all P<0.05). Conclusion: The levels of the serum vitamin E and D, and total bilirubin and indirect bilirubin of the pregnant women with PIH are abnormal, which are related to the family history of hypertension, the urinary protein level, and the prepregnancy body mass index value of the women. There are correlations among the levels of the serum vitamin E and D, and total bilirubin and indirect bilirubin each other.
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