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Value of transvaginal ultrasound combined with the levels of progesterone and β-human chorionic gonadotropin of pregnant women for diagnosing their threatened abortion during the first trimester of pregnancy |
Beijing Aerospace General Hospital, Beijing, 100000 |
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Abstract To analyze the diagnostic value of transvaginal ultrasound combined with the levels of progesterone and β-human chorionic gonadotropin (β-HCG) of pregnant women for their threatened abortion during the first trimester of pregnancy. Methods: A total of 86 pregnant women with threatened abortion during the first trimester of pregnancy were selected in study group, and 90 normal pregnant women during the first trimester of pregnancy were selected in control group from May 2020 to April 2021. The serum P and β-HCG levels of these women were detected. The vaginal ultrasound was used to measure the diameters of their gestational sac and yolk sac, and the values of the resistance index (RI), peak systolic velocity (PSV), and acceleration time (ACT) of the ascending branch of the gestational sac and villous space arterial blood flow. The diagnostic values of vaginal ultrasound and the levels of the serum P and β-HCG for the threatened abortion of these women were analyzed. Results: The values of RI, ACT, and the yolk sac diameter of the women in the study group were significantly higher than those of the women in the control group, while the PSV value, the serum P and β-HCG levels, and the pregnancy sac diameter of the women in the study group were significantly smaller than those of the women in the control group (P<0.05). Receiver operating characteristic curve analysis showed that the area under the curve of the RI value, the PSV value, the ACT value, the sac diameter, the yolk sac diameter, the progesterone level, theβ-HCG level, and the combination of the sac diameter, the yolk sac diameter, the progesterone level, and theβ-HCG level were 0.798, 0.942, 0.658, 0.863, 0.804, 0.920, 0.946, and 0.997, respectively. Conclusion: The area under the curve, the sensitivity, and the specificity of transvaginal ultrasound combined with the levels of the serum P and β-HCG of the pregnant women for diagnosing their threatened abortion during the first trimester of pregnancy are higher, which can improve the diagnostic efficiency of threatened abortion with some clinical application value.
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