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| Value of uterine artery blood flow parameters of pregnant women with unexplained recurrent spontaneous abortion during the first trimester of pregnancy for predicting their spontaneous abortion within 28 gestational weeks |
| Puyang Maternal and Child Health Care Hospital, Henan Province, 457000 |
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Abstract To study the characteristics of uterine artery blood flow parameters of pregnant women with unexplained recurrent spontaneous abortion（URSA ) during the first trimester of pregnancy, and to study its value for predicting the spontaneous abortion of the women. Methods：A total of 272 pregnant women during the first trimester of pregnancy were selected as the research objects from January 2018 to January 2020. Among them，38 singleton women with URSA ≥2 times were in group A，41 women with once spontaneous abortion were in group B，and 193 women without spontaneous abortion history were in group C. The values of uterine artery blood flow parameters of the women during 13 gestational weeks were measured by B-ultrasound，and the different values of pulsatility index(PI)，uterine artery resistance index (RI), and systolic velocity of peak /end diastolic velocity (S/D) of uterine artery blood flow of the women were compared among the three groups. Receiver operator characteristic (ROC) curve was used to evaluate the values of the PI，RI, and S/D values for predicting the spontaneous abortion of the women during 28 gestational weeks, and the critical values of the PI，RI, and S/D were calculated. Results: The PI and RI values had significantly different of the women between group A and group C, and between group B and group C. The S/D value had significantly different of the women between group A and group B, and between group A and group C (P<0.05). There was no significant differences in the values of PI, RI, and S/D of left and right uterine arteries of the women between group A and group B (P>0.05). The spontaneous abortion rate (71.1%) of the women in group A was significantly higher than that (12.2%) of the women in group B and that (5.7%) of the women in group C (P<0.013). ROC curve analysis showed that the values of PI, RI, and S/D of the women during the first trimester of pregnancy had certain predictive and diagnostic value for the their spontaneous abortion occurrence within 28 gestational weeks, and the areas under the curve of which were 0.892, 0.887, and 0.896, respectively, and the critical values of which were 2.25, 0.82, and 8.38, respectively. Conclusion：The spontaneous abortion rate of the pregnant women with URSA is higher. The blood flow parameters values of the pregnant women with URSA during the first trimester of pregnancy are significantly higher than those of normal pregnancy women，and which have certain predictive value for the spontaneous abortion within 28 gestational weeks. It is suggested that clinical intervention can be conducted in the women with URSA based on their uterine blood flow parameters values as the reference indexes to avoid spontaneous abortion.
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| Cite this article: |
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WANG Qiong. Value of uterine artery blood flow parameters of pregnant women with unexplained recurrent spontaneous abortion during the first trimester of pregnancy for predicting their spontaneous abortion within 28 gestational weeks[J]. 中国计划生育学杂志, 2022, 30(5): 1159-.
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| URL: |
| https://www.zgjhsyx.com/EN/ OR https://www.zgjhsyx.com/EN/Y2022/V30/I5/1159 |
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