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| Value of abdominal color ultrasonography combined with serum sex hormone level for diagnosing early ectopic pregnancy |
| 1. Hainan Women and Childrens Medical Center, Haikou，Hainan Province, 570208; 2. Haikou Hospital Affiliated to Xiangya School of Medicine, Central South University |
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Abstract To explore the value of abdominal color ultrasonography combined with serum sex hormone level for differential diagnosing early ectopic pregnancy. Methods: The clinical data of 60 women with ectopic pregnancy (in group A) and 60 women with normal pregnancy (in group B) during April 2019 to March 2021 were collected retrospectively. The serum levels of β- human chorionic gonadotropin (β-HCG), luteinizing hormone (LH), follicular follicular hormone (FSH), and estradiol (E2) of the women in both groups were detected. The endometrial thickness and uterine adnexal characteristics of the women in both groups were examined by abdominal color ultrasound. The differential diagnosis value of abdominal color Doppler ultrasonography combined with serum hormone level for early ectopic pregnancy was calculated based on the final clinical definite diagnosis results. Results: The levels of FSH (31.67±7.88 U/L) and LH (27.16 ± 5.92 U/L) of the women in group A were significantly higher than those (10.48 ± 6.39 U/L and 9.17±3.14 U/L) of the women in group B. The levels of β-HCG (1979.4 ± 592.1 IU/L) and E2 (206.03 ±35.24 pg/ml), and the endometrial thickness (0.85 ± 0.14 cm) of the women in group A were significantly lower than those (2894.1 ± 769.5 IU/L, 875.34±110.61Pg/mol, and 1.17 ± 0.14 cm) of the women in group B. The detection rate of mass of uterine adnexal (81.7%) and pelvic effusion positive rate (70.0%) of the women in group A were significantly higher than those (35.0% and 38.3%) of the women in group B. The detection rate of intrauterine pregnancy sac (15.0%) of the women in group A was significantly lower than that (100.0%) of the women in group B (P＜0.05). The area under the curve of ultrasonography examination combined with four hormone indexes for diagnosing ectopic pregnancy was 0.956, and which missed diagnosis rate (1.7%) and misdiagnosis rate (0) were significantly lower than those of ultrasonography examination or four hormone indexes alone. Conclusion: Abdominal color ultrasonography combined with serum sex hormone detection can greatly improve the diagnostic accuracy of ectopic pregnancy.
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