Abstract To explore the effect of modified Cangfudaotan decoction for treating women with phlegm-dampness blocking anovulatory infertility on the levels of their sex hormone and ovarian artery blood flow indexes.Methods: 96 women with anovulatory infertility due to phlegm-dampness blockade were selected as the research subjects, and these women were divided into control group and observation group (48 cases in each group) according to the random number table method.The women in the control group were given clomiphene citrate capsule, and the women in the observation group were given clomiphene citrate capsule combined with modified Cangfudaotan decoction.The levels of sex hormone and hemodynamic indexes of the women before treatment, in 1 and 4 menstrual cycles after treatment were compared between the two groups.The situations of ovulation and pregnancy of the women in the two groups were followed up for 1 year.Results: After 1 or 4 cycles of treatment, the level of estradiol (E2) of the women in the observation group was significantly higher than that of the women in the control group, while the levels of follicle stimulating hormone (FSH) and luteinizing hormone (LH), and the value of LH/FSH of the women in the observation group were significantly lower than those of the women in the control group.The maximum systolic blood flow velocity (PSV) value of ovarian artery of the women in the observation group was significantly higher than that of the women in the control group, while the values of resistance index (RI) and pulsatile index (PI) of ovarian artery of the women in the observation group were significantly lower than those of the women in the control group (all P<0.05).During 1 year followed up, there was no significant difference in ovulation rate (83.3% vs.75.0%) of the women between the two groups.The pregnancy rate (50.0%) of the women in the observation group was significantly higher than that (29.2%) of the women in the control group (P<0.05).Conclusion: Cangfudaotan decoction for treating infertility women with phlegm-damp block type anovulatory can effectively regulate their levels of sex hormones and improve their blood flow of ovarian arteries, which increases the clinical effect.
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