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| Effect of epidural sufentanil combined with ropivacaine for labor analgesia |
| Guang'an People's Hospital, Sichuan Province, 638000 |
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Abstract To investigate the effect of epidural sufentanil combined with ropivacaine for labor analgesia, and to study its influence on the neonatal physical signs. Methods: A total of 752 pregnant women were selected as the research subjects between August 2018 and December 2019. According to the advices of doctors and the wishes of the women, these women were divided into control group (426 women without labor analgesia) and observation group (326 with epidural sufentanil combined with ropivacaine for labor analgesia). The pain grading criterion of WHO was used to evaluate the analgesia effect of the women in the two groups. The duration of labor stage, the rate of transferring to cesarean section, the postpartum hemorrhage volume, the neonatal physiological indexes, Apgar score, and the incidence of adverse reactions of the women were compared between the two groups. Results: The pain degree of the women in the observation group was significantly lower than that of the women in the control group when the uterine orifice opened to 5 cm and 10 cm. The duration of the first stage of labor (321.3±31.9min) of the women in the observation group was significantly shorter than that (432.6±40.2min) of the women in the control group, but the duration of the second stage of labor (85.7±3.8min) of the women in the observation group was significantly longer than that (54.1±2.7min) of the women in the control group. The rate of transferring to cesarean section (4.0%) and postpartum bleeding volume (122.45±20.0ml) of the women in the observation group were significantly lower than those (11.7% and 126.4± 21.1mL) of the women in the control group. The incidence of neonatal asphyxia (0%) in the observation group was significantly lower than that (2.6%) in the control group (all P<0.05). There were no significant differences in the neonatal physiological indexes (body weight, height, head circumference), Apgar score, and the total incidence of adverse reactions between the two groups (P>0.05). Conclusion: The curative effect of epidural sufentanil combined with ropivacaine for labor analgesia is good, which can significantly shorten duration of the first stage of labor, reduce the rates of transferring to cesarean section and the incidence of neonatal asphyxia, and can decrease the postpartum hemorrhage volume without increasing the adverse influences on the neonatal physiological indexes and quality of life.
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