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| Influence of short acting oral contraceptives and sequential treatment of estrogen and progesterone for treating women after abortion on their endometrial receptivity |
| Langfang Maternal and Child Health Hospital, Langfang, Hebei Province, 065000 |
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Abstract To explore the therapeutic effect on menstrual recovery of short-acting oral contraceptives and sequential treatment of estrogen and progesterone for treating women after abortion, and to study its influence on endometrial receptivity of the women. Methods: A total of 120 women who underwent abortion were selected as the research subjects between April and December 2020. These women were divided into group A (40 women had treated by short-acting oral contraceptives), group B (40 women had treated by sequential treatment of estrogen and progesterone), and group C (40 women had no treated by any hormone drug) by random number table method. The vaginal bleeding time, the menstrual recovery time, the postoperative bleeding volume, the endometrial thickness, the menstrual condition (MDQ score), the levels of sex hormones ［estradiol (E2), luteinizing hormone (LH), follicle stimulating hormone (FSH)］, the complications and adverse reactions rates of the women were compared among the three groups. Results: The vaginal bleeding time, the menstrual recovery time, and the postoperative bleeding amount of the women in group A and group B were significantly lower than those of the women in group C. The endometrial thickness of the women in group B was significantly higher than that of the women in group A or group C. MDQ score of the women in group A and group B were significantly lower than that of the women in group C. The serum E2, LH, and FSH levels of the women in group A and group B were significantly higher than those of the women in group C. The total incidence of complications of the women in group A (5.0%) or group B (5.0%) was significantly lower than that (17.5%) of the women in group C (all P<0.05). There was no significant difference in the incidence of adverse reactions of the women among the three groups (P>0.05). Conclusion: Short-acting oral contraceptives and sequential treatment of estrogen and progesterone for treating the women after abortion both can significantly shorten their vaginal bleeding duration and can promote their menstrual recovery, and sequential treatment of estrogen and progesterone can improve the endometrial receptivity of the women.
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