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Abstract To investigate the influence difference of laparoscopic myomectomy for treating patients with different age on their ovarian function recovery, hemorheological parameters, oxidative damage, and pain situation. Methods: 80 patients who underwent laparoscopic myomectomy from May 2018 to June 2020 were selected as the research objects. These patients were divided into study group(n=37, ≤35 years old) and control group(n=43, >35 years old). Ovarian function indexes, ultrasonic hemorheology indexes, oxidative damage and pain indexes of the patients were observed before and after treatment. Results: After treatment, the levels of serum follicle stimulating hormone and luteinizing hormone of the patients in the two groups had increased significantly, and which of the patients in the study group were significant lower than those of the patients in the control group. The level of serum estradiol of the patients in the two groups had decreased significantly after treatment, and which of the patients in the study group was significant higher than that of the patients in the control group(all P<0.05). The levels of whole blood viscosity, plasma viscosity, and erythrocyte aggregation index of the patients in the two groups had increased significantly after treatment, and which of the patients in the study group were significant lower than those of the patients in the control group. The levels of ischemia-modified albumin, myoglobin, and cyclophosphamide of the patients in the two groups had decreased significantly after treatment, and which of the patients in the study group were significant lower than those of the patients in the control group. The levels of substance P, interleukin-6, and prostaglandin E2 of cardiomyocytes of the patients in the two groups had increased significantly after treatment, and which of the patients in the study group were significant lower than those of the patients in the control group(P<0.05). Conclusion: Laparoscopic myomectomy for treating patients with different age has obvious influence on their ovarian function, and the indexes of hemorheology, oxidative damage, and pain, but which has less influence on the patients equal to or less than 35 years old.
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