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Abstract To explore the value of the score of endometriosis fertility index (EFI) and the serum Resistin level for diagnosing endometriosis complicated with infertility. Methods: 84 women with endometriosis were selected in group A, 47 women with endometriosis and infertility were selected in group B, and 53 healthy women were selected in group C from June 2018 to June 2020. The EFI score and serum Resistin level of the women in the three groups were detected. The value of the combination of the EFI score and serum resistin level of the women for diagnosing endometriosis complicated with infertility was analyzed. Results: The EFI score of the women in group C, group A, and group B had significantly decreased in turn, but the serum Resistin of the women in group C, group A, and group B level had significantly increased in turn (P<0.05). ROC curve analysis showed that the area under curve (AUC), the sensitivity, and the specificity of EFI score for diagnosing endometriosis complicated with infertility were 0.754, 0.727, and 0.792, respectively. The AUC, the sensitivity, and the specificity of serum Resistin level for diagnosing endometriosis complicated with infertility were 0.805, 0.845, and 0.736, respectively. The AUC, the sensitivity, and the specificity of EFI score combined with serum Resistin level for diagnosing endometriosis complicated with infertility were 0.886, 0.864, 0.849, respectively, which were significant higher than that of EFI score or serum Resistin level alone (P<0.05), and the consistency (Kappa=0.726) of which compared to the gold standard of clinical diagnosis was better. The sensitivity, the specificity, the positive predictive value, the negative predictive value, and the accuracy of the gold standard of clinical diagnosis for endometriosis complicated with infertility were 0.861, 0.867, 0.847, 0.879, and 0.864, respectively. Conclusion: EFI score combined with serum Resistin level has some diagnostic value for endometriosis complicated with infertility.
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