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Correlation between the levels of serum high density lipoprotein and homocysteine levels of pregnant women and their severity of preeclampsia |
Qingyang People's Hospital, Gansu Province, 745000 |
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Abstract To investigate the differentiation of serum high density lipoprotein (HDL) and homocysteine (Hcy) levels of pregnant women with different severity of preeclampsia. Methods: 80 pregnant women with preeclampsia were selected in study group from June 2018 to September 2019, which included 40 women with severe preeclampsia in group A and 40 women with mild preeclampsia in group B. 40 normal pregnant women were selected in control group during the same period. The levels of HDL-C and Hcy were detected, and the differentiation of HDL-C and Hcy levels of the women in the three groups was analyzed. Results: There were no significant differences in the low density lipoprotein (LDL) level, the gravidity, the pre-pregnancy body mass index (BMI) value, the systolic blood pressure and diastolic blood pressure values of the women among the three groups, but there were significant differences in the levels of triglyceride (TG), Hcy, HDL-C and LDL-C of the women among the three groups (P<0.05). Univariate analysis showed that the proportions of abnormal Hcy level, the BMI value, and the TG and HDL-C levels of the women in group A was significant higher than those of the women in group B. The Hcy level, the LDL-C level, and the HDL-C level were positively correlated with the severity of preeclampsia (all P<0.05). The regression equation Y=54.79+ 428.25 X. Conclusion: Serum HDL-C and Hcy levels of pregnant women with preeclampsia are correlated with the severity of their preeclampsia, which may provide clinical reference for predicting the disease progression of the pregnant women with preeclampsia.
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