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| Curative and economic analysis of lower uterine breakwater-like suture combined with ergonovine for treating postpartum hemorrhage with placenta previa |
| 1. Hainan Modern Maternity and Infant Hospital, Haikou, Hainan Province, 570203；2. The Second people's Hospital of Hainan Province |
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Abstract To investigate the curative and economic analysis of lower uterine breakwater-like suture combined with ergonovine for treating postpartum hemorrhage of women with placenta previa. Methods: 102 women with placenta previa and postpartum hemorrhage were selected and divided into control group and observation group (51 cases in each group) according to different methods of hemostasis from January 2017 to June 2019. The women in the control group were given lower uterine breakwater-like suture only for hemostasis，and the women in the observation group were given lower uterine breakwater-like suture combined with ergonovine for hemostasis. The blood loss during operation and in postoperative 2 h and 24 h, the total blood loss, the hemoglobin (Hb) level, the red blood cell (RBC) count, the Ca2+ concentration, the coagulation function, the incidence of adverse reactions, the clinical efficacy, and economic analysis of the women were compared between the two groups. Results: The average drug treatment cost (287.7 Yuan) of the women in the observation group was significant lower than that (561.20 Yuan) of the women in the control group. The amount of blood loss during operation and in postoperative 2 h and 24 h, the total blood loss amount, the concentration of Ca2+, and the incidence of adverse reaction of the women in the observation group were significant lower than those of the women in the control group. The H) level and RBC counts of the women in the observation group were significant higher than those of the women in the control group. The drug cost-effectiveness ratio (2.95) of the women in the observation group was significant lower than that (6.41) of the women in the control group. The amount of intraoperative blood loss (361.12±154.31 ml), the amount of blood loss in postoperative 2h (403.51±113.71 ml), and the amount of blood loss in postoperative 24h (467.39±129.68 ml) of the women in the observation group were significant lower than those of the women in the control group (P＜0.05). Conclusion: Lower uterine breakwater-like suture combined with ergonovine for treating women with placenta previa can reduce the amount of blood loss during cesarean section and improve their coagulation function. The incidence of adverse reactions after treatment and the cost of therapy are low.
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