|
Abstract To explore the clinical efficacy of oxytocin combined with calcium gluconate for treating postpartum hemorrhage of women, and to study its influence on their coagulation function. Methods: 198 women with postpartum hemorrhage were selected and were randomly divided into two groups (49 cases in each group) from January 2018 to June 2020. The women in the control group were treated by oxytocin, and the women in the study group were treated by oxytocin combined with calcium gluconate. The treatment efficiency of the women was compared between the two groups. Results: The effective rate of the women in the study group (91.9%) was significant higher than that (83.7%) of the women in the control group. The coagulation indexes ,such as activated partial thromboplastin time (APTT) prothrombin time (PT), and D-dimer (D-D) of the women in the study group were 26.9±3.1s, 11.1±0.2s, and 1.6± 0.2mg /L, which were significant lower than those(28.2±3.4s, 12.1±0.3s, and 1.6± 0.2mg /L) of the women in the control group, but the plasma fibrinogen (FIB) of the women (4.5± 0.7g/L) in the study group was significant higher than that (4.1± 0.6g/L) of the women in the control group. The amount of 2h postpartum bleeding, 24h postpartum bleeding, and the total amount of postpartum bleeding of the women in the study group were 173.6± 16.6ml, 326.2± 46.7ml, and 499.8±31.6 ml, which were significant lower than those (218.4± 20.5ml, 486.5±32.8 ml, and 704.9± 26.7ml) of the women in the control group. The indexes of oxidative stress reaction and inflammatory factors levels of the women in the study group were significant lower than those of the women in the control group, but the serum calcium and hemoglobin levels of the women in the study group were significant higher (all P<0.05). Conclusion: Oxytocin combined with calcium gluconate for treating postpartum hemorrhage has significant effectiveness.
|
|
|
|
|
|
