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| Effect of Kuntai capsule combined with progesterone for treating women with infertility caused by luteal insufficiency |
| Yongchuan District Maternal and Child Health Care Hospital, Chongqing, 402160 |
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Abstract To investigate the effect of Kuntai capsule combined with progestin for treating women with infertility caused by luteal insufficiency, and to study its influence on their endometrial receptivity. Methods: 100 women with infertility caused by luteal insufficiency were selected as the subjects and were divided into two groups according to the random number method from January 2016 to December 2018. 50 women in the observation group were treated with Kuntai capsule combined with progesterone, and the women in the control group were treated with progesterone. The clinical efficacy of the women was compared between the two groups. Results: The effective rate of the women in the observation group (88.0%) was significant higher than that (68.0%) of the women in the control group. The scores of lumbar and knee weakness, hypolibido, chills, listlessness, and edema of lower limbs of the women in the observation group were significant lower than those of the women in the control group. The rising time of basal body temperature (BBT) and the maximum follicle diameter of the women in the observation group were 16.3±4.8d and 19.8±6.2mm, which were significant higher than those (12.9±3.1d and 17.2± 5.0mm) of the women in the control group (all P<0.05). The levels of estradiol, progesterone, and endometrial thickness of the women in the observation group were significant higher than those of the women in the control group, but the pulse index value of the women in the observation group was significant lower. The pregnancy rate (48.0%) of the women in the observation group was significant higher than that (20.0%) of the women in the control group (P<0.05). Conclusion: Kuntai capsule combined with progestin for treating women with infertility caused by luteal insufficiency has significant clinical efficacy, which can improve their endometrial receptivity, improve their pregnancy rate with good safety.
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