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Abstract To explore the effect of Bushen huatan recipe for treating obese women with polycystic ovary syndrome (PCOS), and to study its influence on the insulin resistance index (HOMA-IR), waist-to-hip ratio (WHR) and apolipoprotein level of these women. Methods：110 obese women with PCOS were selected and were divided into two groups from December 2016 to July 2018 (55 cases in each group). The women in the control group were treated with routine ethinylestradiol and cyproterone pills, and the women in the observation group were treated with routine ethinylestradiol and cyproterone pills combined with Bushen huatan recipe.The clinical efficacy of the women in the two groups were analyzed. Results：After treatment, the levels of apolipoprotein-A (1.77±0.56g/L) and serum adiponectin level (10.63± 2.12mg/L) of women in the observation group were significant higher than those of women in the control group, but the level of HOMA-IR (1.58±0.65), BMI value (24.25±3.10kg/m2), WHR value (1.14±0.22), and apolipoprotein-B level (0.45±0.12g/L) of women in the observation group were significant lower than those of women in the control group. The hair score (5.10±1.98 points), acne score (0.31±0.12 points), menstrual disorder score (8.79±1.89 points) of women in the observation group were significant lower than those of women in the control group, but the pregnancy rate (60.0%) of women in the observation group was significant higher than that (40.0%) of women in the control group (all P>0.05). There was no significant difference in the ovulation rate of women between the two groups (P>0.05). Conclusion: Bushen huatan recipe can alleviate the clinical symptoms of obese women with PCOS, regulate their blood lipid levels, reduce their values of HOMA-IR, BMI, and WHR, and increase their pregnancy rate.
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