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| Analgesia effect of dexmedetomidine combined with ropivacaine transversus abdominals plane block after laparoscopic ovarian cyst resection |
| The First People's Hospital of Suzhou, Anhui Province, 234000 |
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Abstract To investigate the postoperative analgesic effect of dexmedetomidine (Dex) combined with ropivacaine transversus abdominals plane block of laparoscopic ovarian cyst resection. Methods: From January 2018 to October 2020, 94 women who had undergone laparoscopic ovarian cyst resection were selected and were divided into study group and control group according to the random number table. All of the women had received general anesthesia, and ultrasoundguided transverse abdominals plane block was performed at the end of the operation. The women in the study group were injected into the transverse abdominal muscle with 40ml of Dex 0.5 μg/kg combined with 0.25% ropivacaine, and the women in the control group were injected into the transverse abdominal muscle with 40 ml of 0.25% ropivacaine only. The hemodynamic indexes, pain score, analgesic effect, and adverse reactions rate of the women were compared between the two groups. Results: There were no significant differences in blood pressure value and heart rate of the women between the two groups during and after operation (P>0.05). VAS score of the women in the study group at postoperative 6 h, 12 h were 1.18±0.56 points and 1.70±0.61 points, which were significant lower than those of the women in the control group. The pressure times by self-control effective analgesia (5.3±1.7 times), awakening time (3.2±0.6 min), spontaneous breathing recovery time (3.7±0.9 min), and the extubation time of laryngeal mask (4.3±0.8 min) of the women in the study group were significant less than those of the women in the control group, but the time of analgesia pump pressed for the first time (21.5±7.7 h) and the time of sensory blockade (8.4±1.5 h) of the women in the study group were significant longer. The dosage of fentanyl used (362.78±103.42μg) and propofol used (65.76±16.30g/kg/min) of the women in the study group at 24h after surgery were significant less than those of the women in the control group (P<0.05), and the total incidence of adverse reactions (8.5%) of the women in the study group had no significant different from that (12.8%) of the women in the control group (P>
0.05). Conclusion: Dex combined with ropivacaine transversus abdominis plane block can improve the postoperative analgesia effect of the women after laparoscopic ovarian cyst resection, and prolong their analgesic time, which can facilitate their postoperative recovery.
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