To investigate the relationship between endometriosis syndrome and endometrial polyps of infertility patients, and to study the endometrial hyperplasia situation. Methods: Infertility patients were selected and divided into study group (68 patients with endometriosis) and control group (42 patients without endometriosis) according to the results by B-ultrasound examination from January 2015 to March 2018. The incidence of endometrial polyps, pregnancy rate within 18 months after treatment, and pathological result of endometrial polyps of patients in the two groups were analyzed. Spearman correlation coefficient analysis was used to analyze the correlation between endometriosis of infertile patients and the occurrance of endometrial polyps. Results: The incidence of endometrial polyp of the study group was 75.0% (51/68), which was significant higher than that (23/42, 54.8%) of the control group (P<0.05). The proportion of patients with polyps in the study group was 75.0% (51/68), which was significant higher than that (23/42, 54.8%) of patients in the control group, and the proportion of patients with normal endometrium in the study group was 5.9% (4/68), which was significant lower than that (14/42, 33.3%) of patients in the control group (P<0.05). Correlation analysis showed that endometriosis syndrome rate was positively correlated with the development of endometrial polyps of infertile patients (P<0.05). In the study group, the total pregnancy rate within 18 months after treatment of patients with endometrial polyp was 80.4% (41/51), which was significant higher than that (10/17, 58.8%) of patients without endometrial polyp (P<0.05). In the control group, the total pregnancy rate within 18 months after treatment of patients with endometrial polyp was 69.6% (16/23), which had no significant different from that (14/19, 73.7%) of patients without endometrial polyp (P>0.05). Conclusion: Endometriosis of infertility patients is proportional to the incidence of endometrial polyps, which suggested that clinical diagnosis and treatment endometriosis should be paid more attention endometrial polyp.