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| Clinical efficacy of cervical Cook ripening balloon combined with oxytocin infusion or dinoprostone for induced labor of primiparas in term pregnancy |
| Hubei Maternal and Child Health Care Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei Province,430000 |
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Abstract To analyze the efficacy and safety of cervical Cook ripening balloon combined with oxytocin infusion or dinoprostone for induced labor of primiparas in term pregnancy. Methods: 345 primiparas were selected and were randomly divided into control group and research group according to the random number table from June 2017 to June 2018. 180 primiparas in the control group were given dinoprostone for induced labor, and 165 primiparas were given cervical Cook ripening balloon combined with oxytocin infusion for induced labor. The effects of promoting cervical ripening, Bishop scores before and after treatment, duration of labor, rate of adverse reactions during induced labor, and prognosis of primiparas were compared between the two groups. Results: Bishop score of primiparas in the two groups had decreased significantly after treatment, but there was no significant difference between the two groups. There was no significant difference in the total effective rate of promoting cervical ripening (94.6% vs.91.1%) of primiparas between the two groups (all P>0.05). There were no difference in the duration from induced labor begain to near to labour, and the vaginal delivery rate within 48 hours of primiparas between the two groups (P>0.05). The rate of vaginal delivery within 24 hours of primiparas in the research group was 51.5%, which was significant lower than that (70.0%) of primiparas in the control group (P<0.05). The incidences of emergency labor because of uterine hyperstimulation and drugs/balloon withdrawal because of abnormal fetal heart monitoring of primiparas in the research group were 0.6% (1 case) and 0.6% (1 case), which were significant lower than those ［4.4% (8 cases) and 6.7% (12 cases)］ of primiparas in the control group (P<0.05). There were no significant different in the rates of intrapartum fever and postpartum hemorrhage, and neonatal Apgar score and umbilical artery PH value between the two groups (P>0.05). Conclusion: The cervical Cook balloon combined with oxytocin for promoting cervical ripening and improving induced labor has the same success rate of dinoprostone used, which does not increase the risk of puerperal infection, and can reduce adverse reactions such as abnormal fetal heart and uterine hyper stimulation during induced labor.
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