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Abstract Objective: To investigate the influence of standardized treatment of pregnant women with gestational diabetes mellitus (GDM) on maternal and infant comprehensive indicators during pregnancy and lactation. Methods: 186 pregnant women with GDM were enrolled and were randomly divided into observation group and control group by table of random numbers from January 2017 to January 2018. The 95 women in the control group had received routine pregnancy management, and 91 women in the observation group had received standardized treatment. The pregnancy outcomes of women were compared between the two groups, and the metabolic related indicators of all women were detected during pregnancy, delivery, and lactation (till to 90 days after delivery). Results: After treatment, the adherence score, score of disease/health knowledge, and rate of dietary to standard of women in the observation group were significant higher than those of women in the control group(P<0.05). The levels of FPG, 2hPG, HbAlc, TC, TG and LDL-C, and the cesarean section rate, the incidence of PHD, the abnormal rates of glucose and lipid metabolism, the incidences of macrosomia and neonatal hypoglycemia, the weight gain during pregnancy, the retention rates of of BMI and body weight of women in the observation group were significant lower than those of women in the control group before delivery and 90 days after delivery, while the levels of HDL-C, TP and ALB of women in the observation group were significantly higher (all P<0.05). Conclusion: Standardized treatment of women with GDM is beneficial to improve the metabolic status of women during pregnancy and lactation, and can improve the clinical outcomes of mother and infant.
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