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| The clinical effect of microdissection of testicular sperm extraction for treating patients with non-obstructive azoospermia |
| 1. Hebei Science and Technology Academy of Family Planning, Key Laboratory of Family Planning and Eugenics, National Health commission / Key Laboratory of Reproductive Medicine, Shijiazhuang, Hebei Province, 050000; 2. Bethune International Peace Hospital |
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Abstract Objective: To investigate the clinical effect of microdissection of testicular sperm extraction (micro-TESE) for treating patients with non-obstructive azoospermia (NOA). Methods: The clinical data of 60 patients with NOA treated by micro-TESE (in group A) and 48 patients with obstructive azoospermia (OA) treated by testicular puncture (in group B) from July 2017 to December 2018 were analyzed retrospectively. The wives of the patients in the two groups received IVF-ET by intracytoplasmic sperm injection (ICSI). The effect of assisted pregnancy, changes of sex hormone levels of patients before and after NOA treatment were compared between the two groups. Results: The levels of FSH and LH of patients in group A were significant higher than those of patients in group B, but T level and sperm acquisition rate (SRR) of the patients in group A were significant lower than those of patients in group B (P<0.05). In 1 month and 6 months after operation, the levels of FSH and LH of patients in the two groups had no significant different (P>0.05), but T level and IIEF-5 scores had decreased significantly (P<0.05). Conclusion: Micro-TESE can provide opportunity for some patients with NOA to have their own biological offspring, which has high success rate of sperm extraction without obvious complications, but it may damage the testicular function of patients to some extent.
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