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Abstract Objective: To study the effect of different laparoscopic surgeries for treating women with ovarian mature teratoma, and to analyze its influence on their ovarian reserve function. Methods: 64 women with ovarian mature teratoma were selected and were divided into study group and control group by random number method (32 cases in each group) from October 2015 to June 2017. The women in the study group were treated with two-hole laparoscopic surgery, while the women in the control group were treated with three-hole laparoscopic surgery. The operative indexes, the postoperative curative effect, and the incidence of complications of women in the two groups were analyzed. The levels of basic follicle stimulating hormone (FSH), estradiol (E2), and luteinizing hormone (LH) were measured by radioimmunoassay, the levels of antimullerian hormone (AMH) and inhibin B (INHB) were determined by ELISA, and the surgical ovarian volume and antral follicle count (AFC) were measured by ultrasonography. Results: The amount of intraoperative blood loss, time to bed and hospital stay of women in the study group were significant lower than those of women in the control group (P<0.05). One year after the operation, the total effective rate of women in the study group was 93.8%, which was significant higher than that (71.9%) of women in the control group, but the complication rate of women in the study group was 6.3%, which was significant lower than that (25.0%) of women in the control group. After operation, the levels of FSH, E2, LH, and AFC, and ovarian volume of women in the two groups had decreased significantly, and the levels of FSH, E2, LH of women in the study group were significant lower than those of women in the control group, but ovarian volume of women in the study group was significant higher. After operation, the levels of AMH and INHB of women in the study group were significant higher than those of women in the control group (P<0.05). Conclusion: Two-hole laparoscopic surgery for treating women with ovarian mature teratoma has a better therapeutic effect, which can reduce the incidence of postoperative complications and improve the recovery of ovarian reserve function.
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