|
|
|
| The influence of diphereline combined with Danqi fukang oral paste for treating women with endometriosis on their levels of serum COX-2 Flk-1 and inflammatory factors |
| Miyun Teaching Hospital, Capital Medical University, Beijing, 101500 |
|
|
|
Abstract Objective: To investigate the influence of diphereline combined with Danqi fukang oral paste for treating women with endometriosis on their levels of serum COX-2 Flk-1 and inflammatory factors. Methods: 100 women with endometriosis were randomly divided into contral group and study group (50 cases in each group) by the digital table method from March 2016 to March 2018. The women in the control group were treated by diphereline, and the women in the study group were treated by diphereline combined with Danshen fukang oral paste. The clinical efficacy, the levels of serum COX-2, Flk-1 and inflammatory factor, VAS pain score, and the rate of adverse reaction of women in the two groups were observed. Results: The effective rate of women in the study group was 94.0%, which was significant higher than that (66.0%) of women in the control group, but the serum levels of cox-2, flk-1, il-6 and il-8 of women in the study group were significant lower. After treatment,the VAS scores of women on the fifth day, the 20th day, and the 60th day were 4.3±1.4 points, 1.1±1.2 points, and 0.6±0.2 points, respectively, which were significant lower than those (7.0±1.3 points, 7.0±1.3 points, and 7.0±1.3 points, respectively)of women in the control group. The incidence of adverse reactions of women in the study group was 12.0%, which was significant lower than that (32.2%) of women in the control group (P<0.05). Conclusion: Diphereline combined with Danqi fukang oral paste for treating women with endometriosis can significantly increase the efficacy, and can reduce the levels of serum COX-2, Flk-1 and inflammatory factor, and the rate of adverse reaction.
|
|
|
|
|
|
|
|
|
