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| Relationship between vaginal secretion interleukin-8 level of pregnant women with genital tract infection by no streptococcus lactis and their pregnancy outcomes |
| Xilingol League Hospital, Inner Mongolia, 013800 |
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Abstract Objective: To investigate the characteristics of vaginal secretion interleukin-8 (IL-8) level of pregnant women with genital tract infection by no streptococcus lactis, and its relationship with pregnancy outcomes. Methods: 105 pregnant women with genital infection by tract no streptococcus lactis were selected in study group, which included 62 women with premature rupture and 43 women without premature rupture of membrane, and included 36 women with IL-8 level <800ng/L and 69 women with IL-8 level ≥800 ng/L. And other 100 normal pregnant women were selected in control group. The vaginal secretion IL-8 levels of all included women were detected and followed up to delivery. The adverse pregnancy outcomes of all women were counted. Results: The IL-8 level of women in study group was 1032.62±402.35 ng/L, which was significant higher than that（35.51±52.69 ng/L）of women in the control group (P<0.05). In study group, the level of IL-8 of women with premature rupture of membrane was 1235.62±529.37 ng/L, which was significant higher than that（739.92±319.07 ng/L）of women without premature rupture of membrane (P<0.05). The incidences of intrauterine growth retardation, puerperal infection of women and neonatal infection in the study group was significant higher than those in the control group (P<0.05). In study group, the neonatal infection rate of women with without premature rupture of membrane was significant higher than that of women without premature rupture of membrane (P<0.05). The neonatal infection rate of women with IL-8 level ≥800 ng/L was 24.2%, which was significant higher than that（5.6%）of women with IL-8 level ≥800 ng/L (P<0.05). Conclusion: The level of IL-8 in vaginal secretions of pregnant women with genital tract no streptococcus lactis infection is significantly increased during the third trimester pregnancy, and the vaginal secretion level of IL-8 is closely related to premature rupture of membranes and neonatal infection. Detection of vaginal secretions IL-8 level of preganant women can help predict the genital tract infection by no streptococcus lactis and help prevent abnormal pregnancy outcomes.
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