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| The influence of laparoscopic uterine vascular occlusion combined with hysteromyomectomy on ovarian function, quality of life, and reproductive function of women with hysteromyoma |
| 1.Jiangbei Hospital of Zhongda Hospital Affiliated to Southeast University(Nanjing Dachang Hospital),Jiangsu Province,210043；2. Zhongda Hospital Affiliated to Southeast University |
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Abstract Objective: To explore the influence of laparoscopic uterine vascular occlusion combined with hysteromyomectomy on ovarian function, quality of life and reproductive function of women with hysteromyoma. Methods: The data of 76 women with hysteromyoma from Feb.2016 to April 2017 were collected. 35 women in control group had experienced laparoscopic hysteromyomectomy, and 41 women in study group had experienced laparoscopic uterine vascular occlusion combined with hysteromyomectomy. The levels of follicle stimulating hormone (FSH), the estradiol (E2) and the luteinizing hormone (LH), and score of quality of life scale (SF-36) were compared between the two groups. The rates of pregnancy and the recurrence of women in the two groups were recorded. Results: The bleeding volume during operation, the time of the exhaust, and the rate of complications of women in the syudy group were significant lower than those of women in the control group (P<0.05). There were no significant different in the levels of E2, LH, and FSH of women before and 12 months after operation between the two groups (P>0.05). 2 months after operation, E2 level of women in the study group had significantly decreased, levels of LH and FSH had significantly increased, and there were significant different in the levels of E2, LH, and FSH of women 2 months after operation between the two groups (P<0.05). The score of SF-36 of of women in the syudy group were significant lower than those of women 12 months after operation in the control group (P<0.05). The pregnancy rate of women in the study group was 72.4% (21/29), which had no significant different from that (68.0%, 17/25) of women in the control group (P>0.05). The pregnancy rate of women in the study group was 2.4% (1/41), which was significant lower than that (8.6%, 3/35) of women in the control group (P<0.05). Conclusion: The laparoscopic uterine vascular occlusion combined with hysteromyomectomy for threating women with hysteromyoma has good effect, has no any adverse influence on the reproductive function, and can promote the quality of life. It maybe has slight and transient adverse effect on the ovarian function of women, but the ovarian function will be recovered gradually.
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