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| A analysis of maternal and infant outcomes of women with early onset severe preeclampsia at different pregnancy termination timing |
| People's Hospital of Fuyang, Anhui Province, 236000 |
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Abstract Objective: To explore the influence of different pregnancy termination timing on maternal and infant outcomes of women with early onset severe preeclampsia. Methods: 64 cases of pregnant women with early onset severe preeclampsia from were included from February 2013 to October 2018, and were divided into group A (20women were terminated pregancy during <32 gestational weeks), group B (23 women were terminated pregancy during 32 to 33+6 gestational weeks), and group C (21 women were terminated pregancy during≥34 gestational weeks). All included women were given personalized treatment planning after evaluated. The clinical situation, mode of delivery, complications during pregnancy and perinatal adverse outcomes of women were compared among the three groups. Result: The gestational weeks when onset severe preeclampsia, the delivery gestational weeks, and duration of expectant treatment of women in Group C were the highest, and those of women in group A were the lowest (P< 0.05). The rate of cesarean section of women in Group A was lowest, but the rate of induced labor by oxytocin was highest (P<0.05). There were no significant different in rates of vaginal delivery and complication during pregnancy among the three groups (P>0.05). The stillbirth rate, neonatal mortality rate, and incidence of fetal respiratory distress syndrome of women in group A were the highest (P<0.05), but there was no difference in the perinatal asphyxia rate among the three groups (P>0.05). Conclusion: Terminating pregnancy of women with early onset severe preeclampsia at different timing can impact on maternal and infant outcomes. Expectant treatment can be conducted in women with early onset severe preeclampsia when their disease is stable. If the complications are serious, timely terminating pregnancy should be considered to improve maternal and infant outcomes.
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