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| The value of ultrasound elastography combined with color Doppler ultrasound for diagnosing benign or malignant axillary lymph nodes of patients with breast cancer |
| 1. Yuhang District Maternal and Child Health Care Hospital, Hangzhou, Zhejiang Province,311100；2. The Second Affiliated Hospital of Medical College, Zhejiang university |
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Abstract Objective: To explore the value of ultrasound elastography combined with color Doppler ultrasound for diagnosing benign or malignant axillary lymph nodes of patients with breast cancer. Methods: 69 patients with breast cancer were included, and had undergone color Doppler ultrasonography and ultrasound elastography. The value of ultrasound elastography and color Doppler ultrasound for diagnosing benign or malignant axillary lymph nodes of patients with breast cancer was analyzed based on the pathological results as gold standard. There were 28 patients with benign nodules (group A) and 41 patients with malignant nodules (group B) according to the pathologically results. Results: The L/S ratio of axillary lymph node of women in group A was significant higher than that of women in group B (P<0.05). There was no significant different in blood flow resistance index of patients between the two groups (P>0.05). The characteristic of CDFI blood flow of patients in group A was mainly portal type, but that of patients in group B was mainly peripheral type (P<0.05). The axillary lymph node elasticity scores of patients in group A was mainly 1-2 points, which was significantly different from that (3-4 points ) of women in group B (P<0.05). The sensitivity and specificity of color Doppler ultrasound for diagnosing benign or malignant axillary lymph nodes were 67.9% and 63.4%, the sensitivity and specificity of ultrasound elastography for diagnosing benign or malignant axillary lymph nodes were 82.1% and 75.6%, and the sensitivity and specificity of color Doppler ultrasound combined ultrasound elastography for diagnosing benign or malignant axillary lymph nodes were and 92.9% and 97.6%. The area under the curve of color Doppler ultrasound, ultrasound elastography, and color Doppler ultrasound combined ultrasound elastography were 0.719, 0.830, and 0.922, respectively. Conclusion: Ultrasound elastography combined with color Doppler ultrasound can effectively identify the benign or malignant axillary lymph nodes of breast cancer and can determine whether lymph node metastasis occurs, which provides evidence for clinical treating patients with breast cancer.
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