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| The value of maternal coagulation function and umbilical cord blood flow parameters for predicting idiopathic fetal growth restriction |
| Duodao People's Hospital of Jingmen City, Hubei Province, 448000 |
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Abstract Objective: To analyze the value of maternal coagulation function and umbilical cord blood flow parameters for predicting idiopathic fetal growth restriction (IFGR) of pregnant women. Methods: 47 women with IFGR were selected in study group, and 55 normal pregnant women were selected in control group. The levels of maternal hematocrit (HCT), hemoglobin (Hb), fibrinogen (Fbg), plasminogen (Plg), prothrombin time (PT), thrombin time (TT), antithrombin (AT III), d dipolymer (D-D), umbilical artery pulsation index (PI) and resistance index (RI), and the ratio of maximum blood flow velocity in systole to that in end diastole (S/D) of women were compared between the two groups. The value of above indicators for predicting IFGR of pregnant women was analyzed. Results: The levels of Fbg and Plg of women in the study group were significant higher than those of women in the control group, and AT III level was significant lower (P<0.05). There were no statistically significant difference in levels of HCT, Hb, PT, TT, and D-D of women between the two groups (P>0.05). The values of umbilical artery blood flow PI, RI, and S/D of women in the study group were significant higher than those of women in the control group (P<0.05). The IFGR can be predicted by PI, RI and S/D values of fetal umbilical artery (P<0.001). Conclusion: Some maternal coagulation indexes and umbilical cord blood flow parameters of women with IFGR may be abnormally changed. The umbilical cord blood flow parameters, especially RI value, can better predict the occurrence of IFGR.
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