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| The value of quantitative parameters of dynamic contrastenhanced scanning MR for diagnosing ovarian tumors |
| Wenzhou Integrated Traditional Chinese and Western Medicine Hospital, Zhejiang Province, 325000 |
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Abstract Objective: To investigate the value of semi-quantitative parameters and quantitative parameters of dynamic contrast-enhanced scanning MR for diagnosing ovarian tumors. Methods: The clinical data of 82 patients with ovarian tumor were retrospectively collected from January 2010 to May 2018. All patients underwent dynamic incremental scan to obtain semi-quantitative parameters (SI60%, TTP200s) and quantitative parameters (Ktrans, Kep, Ve value). The semi-quantitative parameters and quantitative parameters were compared between the women with benign and with malignant ovarian tumors based on the pathological diagnosis results. ROC analysis used to study the value of SI60%, TTP200s, Ktrans, Kep, and Ve value for differential diagnosing benign or malignant ovarian tumors. Results: A total of 52 women with malignant ovarian tumors and 30 women with benign tumors were detected. The TIC classification of women with benign tumors was mainly type I and type II, which was significant different from that (mainly type II and type III) of women with malignant tumor (P<0.05). The TTP200s, Ktrans, Kep and Ve values of women with benign tumor were significant higher than those of women with malignant tumor (P<0.05), but SI60% of women with benign tumor was significant lower than that of women with malignant tumor (P<0.05). The area under the curve of SI60%, TTP200s, Ktrans, Kep, Ve for diagnosing malignant ovarian tumors was 0.780 (95% CI: 0.664-0.897, P=0.000), 0.869 (95% CI: 0.7650.973, P=0.000), 0.922 (95% CI: 0.853-0.991, P= 0.000), 0.808 (95% CI: 0.699-0.917, P=0.000), and 0.872 (95% CI: 0.768-0.976, P=0.000), respectively. The sensitivity and specificity of diagnosing malignant ovarian tumors were 93.7% and 78.3% when SI60%>96.05%, and the sensitivity and specificity of diagnosing malignant ovarian tumors were 96.4% and 70.3% when TTP200>115s, the sensitivity and specificity of diagnosing malignant ovarian tumors were 87.50% and 92.35% when Ktrans>2535, the sensitivity and specificity of diagnosing malignant ovarian tumors were 78.3% and 91.1% when Kep>0.420, and the sensitivity and specificity of diagnosing malignant ovarian tumors were 69.4% and 90.3% when Ve>0.081. Conclusion: There are significant different in the values of dynamic enhanced scanning parameters (SI60%, TTP200s, Ktrans, Kep, and Ve) for diagnosing benign or malignant ovarian tumors, which are effective imaging indicators for differential diagnosis of benign or malignant ovarian tumors.
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