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Abstract To investigate the change of serum level of anti mullerian hormone (AMH) of women before and after hysterectomy, and to study its clinical value for evaluating ovarian function. Methods: 60 women who experienced hysterectomy from May 2015 to May 2016 were selected as the study objects, and they were divided into control group and study group according to different surgical methods (30 cases in each group). The women in study group underwent laparoscopic hysterectomy, and women in control group underwent conventional open hysterectomy. The blood loss, operation time, exhaust time and hospitalization time of women in both groups were recorded. The ovarian reserve parameters such as levels of FSH, E2, LH and AMH, and basal follicle number of all women were detected. All postoperative women were followed up for half a year and the complications of women were compared between the two groups. Results: The intraoperative bleeding volume, operation time, exhaust time, and hospitalization time of women in study group were significant lower than those of women in control group (P<0.05).The levels of serum E2 and AMH of all women decreased after operation, and the levels of serum FSH and LH of all women increased. The number of basal follicles of women in control group decreased more than that of women in study group (P<0.05). The incidence of complications of women in study group was significant lower than that of women in control group (P<0.05). Conclusion: The serum AMH level of women decreases after hysterectomy, but the change range of women experienced laparoscopic hysterectomy group is less than that of women with conventional open hysterectomy, so laparoscopic hysterectomy has less influence on ovarian function, and it should be popularized in clinic.
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