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Abstract To compare the difference of clinical features and therapeutic methods between women with persistent cesarean scar pregnancy (PCSP) and women with normal cesarean scar pregnancy (NCSP). Methods: The data of 89 women with cesarean scar pregnancy (CSP) from December 2014 to December 2017 were retrospective analyzed, and these 89 women were divided into PCSP group (15 cases) and NCSP group (74 cases). The differences of general situation and clinical therapeutic of women were compared between the two groups. Results: The times of cesarean and the interval time from the last cesarean of women had no statistically significance different between the two groups（P＞0.05）. Compared to those of women in NCSP group, the women in PCSP group were older, their abortion times was more, their average menopause days was longer, lump diameter of scar was longer, scar was thinner, the rate of III CSP was higher, and the time of resume HCG level recovered to normal was shorter (P<0.05). The rate of needing laparotomy resection and repair of the cesarean scar of women in PCSP group was significant higher than that of women in NCSP group (P<0.001). Conclusion: The women with PCSP are more likely to develop to III CSP, and the probability of needing surgical treatment is increased, which should be paid more attention to by clinicians. The diagnosis early and initial treating CSP successfully can reduce the incidence of PCSP.
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