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Abstract To investigate the influence of individualized medical nutrition therapy (IMNT) on glycolipid metabolism index and pregnancy outcomes of women with borderline gestational glucose intolerance (BGGI). Methods: 1200 pregnant women with BGGI were randomly divided into observation group and control group (600 cases in each group). The women in control group had received routine oral diet and exercise guidance, and the women in observation group had received IMNT. The maternal and fetal outcomes were compared between the two groups. The glycolipid metabolism indexes (the level of FPG, 2hPG, HbAlc, TG, TC, HDL-C, and LDL-C) of all included women were measured before intervention, before labor and 12 weeks after delivery. Results: There were 580 pregnant women were eventually enrolled in observation group lastly, and there were 569 pregnant women in control group lastly. The cesarean section rate, incidence of GDM and macrosomia, neonatal birth weight, and Apgar score of pregnant women in observation group were significant lower than those of pregnant women in control group (P<0.05).Before labor and at 12 weeks after delivery, the levels of FPG, 2hPG, HbAlc, TC, TG and LDL-C of pregnant women in observation group were significant lower than those of pregnant women in control group, and level of HDL-C of pregnant women in observation group was significant higher than that of pregnant women in control group (P<0.05). Conclusion: IMNT intervention is beneficial to improve the maternal and child outcomes of pregnant women with BGGI, which can improve the glycolipid metabolism during pregnancy, and can promote pregnancy outcomes.
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