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Abstract Objective: To evaluate the effect of preemptive analgesia with flurbiprofen axetil on pain management of patients after painless induced abortion. Methods：219 patients who experienced painless induced abortion in Beijing obstetrics and gynecology hospital in August 2017 were selected as the subjects of this study. The patients in preemptive analgesia group and in control group were all given combined anesthesia with propofol and remifentanil for surgical abortion. Before abortion,sodium lactate Green's solution were infused intravenously 10 minutes before operation in both groups, and 100 mg flurbiprofen ester was added in the preemptive analgesia group. The visual analogue scale (VAS) of postoperative pain of patients was compared between the two groups, and the clinical effect of preemptive analgesia on pain management of patients after painless induced abortion was preliminarily evaluated. Results: The operation time of patients in preemptive analgesia group was 3.8±1.1 min, while that of patients in control group was 4.5±2.0 min, which had statistically significant different(P<0.05). The VAS scores of patients in preemptive analgesia group at 10 min, 20 min, 30 min and 24 h after operation were 0.0(0.0，1.0), 0.0(0.0，1.0), 0.0(0.0，0.0), 0.0(0.0，0.0), respectively, and the VAS scores of patients in control group at 10 min, 20 min, 30 min and 24 h after operation were 1.0(0.0, 2.0), 1.0(0.0, 2.0),0.0(0.0，1.0), 1.0(0.0, 2.0), respectively. The VAS score of patients in preemptive analgesia group at different time was significant lower than that of patients in control group (P<0.05). Conclusion: Preemptive pain can effectively reduce pain of patients after painless induced abortion, which is a safe and effective mode of analgesia for clinical popularization and application.
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