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| Efficacy and safety of bilateral uterine artery embolization combined with curettage for treating patients with uterine scar pregnancy |
| Jiangbei People's Hospital of Nanjing City (Affiliated Hospital of Nantong University), Nanjing, Jiangsu Province,210000 |
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Abstract Objective: To explore the efficacy and safety of bilateral uterine artery embolization combined with curettage for treating patients with uterine scar pregnancy. Methods: A total of 86 patients with uterine scar pregnancy after history cesarean section in Jiangbei people's hospital were selected from January 2014 to January 2018. All patients were randomly divided into 2 groups (43 cases in each group). The patients in study group were treated by bilateral uterine artery embolization combined with curettage, while the patients in control group were treated by methotrexate combined with curettage. In 3 months after abortion, the clinical symptoms, level of blood-human chorionic gonadotropin (β-HCG), and rate of adverse reaction were compared between the two groups. Results: Compared with those of patients in control group, the disappearance time of the tumor, the duration of vaginal bleeding, the recovery of normal menstrual time postabortion, the continuous vaginal bleeding time, the amount of bleeding during operation, and the level of peripheral blood β-HCG of patients in study group had significantly reduced (P<0.05), and the time of vaginal bleeding after operation of patients in study group had significantly increased (P<0.05). In control group, there were 11 patients (25.6%) with the postoperative pain, 6 patients (14.0%) with gastrointestinal reactions, 6 patients (14.0%) with fever, 4 patients (9.3%) with pelvic infection, and 2 patients (4.7%) with lower extremity venous thrombosis. And in study group, there was no case of pelvic infection and lower extremity venous thrombosis, and there were 4 patients (9.3%) with postoperative pain, 1 patient (2.3%) with gastrointestinal reactions, and 1 patient (2.3%) with fever. Compared with that of patients in control group, the patients in study group had fewer postoperative pain, gastrointestinal reactions and fever (P<0.05). Conclusion: Bilateral uterine artery embolization combined with curettage is effective for treating patients with uterine scar pregnancy, which has good cure rate. The uterine scar pregnancy disappears rapidly, the duration of vaginal bleeding is shorter, and the other clinical indicators are effectively improved.
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