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Abstract Objective: To explore the effect of improved B Lynch suture combined with oxytocin for treating postpartum hemorrhage and its influcence on serum sex hormone levels. Methods: The clinical data of 96 women with postpartum hemorrhage after cesarean section who received therapy in Haining people's hospitalof Zhejiang province from January 2014 to January 2016 were retrospective analyzed. The women treated by oxytocin only were included in control group, and the women treated by improved B Lynch suture combined with oxytocin were included in observation group. The condition of perioperative and bleeding were compared between the groups.The changes of levels of estradiol (E2), follicle stimulating hormone (FSH) and luteinizing hormone (LH) of women after postpartum 1 months or six months were compared, and the rate of postpartum complications of women when followed up for half year was also compared between the groups. Results: The hemostasis time［（6.8±1.0）min］ and hospitalization time［（4.6±0.7）d］ of women in observation group were significant shorter than those［（34.58±3.38）min and（6.7±0.9）d］ of women in control group. The number of blood transfusion［8.3%（4/48）］ and hysterectomy［ 0.0%（0/48）］were significant less than those ［27.1%（12/48）and 12.5%（6/48）］of women in control group (P<0.05).The valum of bleeding intraoperative［（368.6±31.0）ml］, postpartum 12h ［387.4±29.3）ml］, postpartum 24h ［（432.8±27.9）ml］ of women in observation group were significant less than those ［（475.9±34.5）ml，（510.5±31.4）ml，and（552.1±25.1）ml］of women in control group (P<0.05). The rate of bleeding of women in observation group［8.3%（4/48）］was significant less than that of women ［31.3%（15/48）］in control group (P<0.05).After postpartum 1 months and six months, there were no significant different in levels of E2, FSH and LH between the two groups (P＞0.05). During the postpartum half year followed up, the incidence of anemia［6.3%（3/48）］ and rate of intrauterine infection［2.1%（1/48）］ of women in observation group were significant less than those ［20.8%（10/48）and 16.7%（8/48）］of women in control group (P<0.05). Conclusion: Improved B Lynch suture combined with oxytocin for treatment of postpartum hemorrhage has good effect, which can significantly reduce the amount of postpartum hemorrhage, and does not influeny the level of serum sex hormone, so it’s worthy of clinical application.
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