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| Clinical significance of serum uric acid monitoring in pregnant women with hyperuricemia |
| Xinchang People's Hospital, Zhejiang, 312500 |
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Abstract Objective: To explore the clinical significance of serum uric acid monitoring in pregnant women with gestational hypertension and its effect on pregnancy outcome. Methods: From April 2015 to April 2016, 150 women with pregnancyinduced hypertension in Xinchang people's hospital were divided into 72 women in high uric acid blood group and 78 women in normal uric acid group according to their serum uric acid level. 74 healthy pregnant women who selected for prenatal examination in the same period were in normal control group. Change of serum uric acid levels and pregnancy outcomes were compared among the three 3 groups. Results: Serum uric acid level of pregnant women with gestational hypertension was higher than that of women in normal control group, and the serum uric acid level became higher and higher followed the blood pressure increased (P<0.05). The rate of cesarean section, premature delivery, premature rupture of the membranes, early abruption of the placenta and fetal distress of women in high uric acid group were all significant higher than those of women in normal uric acid group and in normal control group (P<005). Conclusion: The uric acid level of pregnant woman with gestational hypertension disease increases following the severity of hypertension and ascension, which also increases the risk of adverse pregnancy outcomes. The dynamic monitoring of blood uric acid level plays an important role in gestational hypertension disease assessment, and it should be paid close attention to in clinical.
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