To analyze and evaluate the application effect of the empowerment education under the staged management model combined with the need hierarchy nursing for patients with laparoscopic ovarian tumor excision during perioperative period. Methods: 105 patients with laparoscopic ovarian tumor excision in the hospital from July 2020 to July 2023 were selected and were randomly divided into control group (n=52) and study group (n=53). The patients in the control group were given the routine nursing model, while the patients in the study group received the empowerment education under staged management model combined with the need hierarchy nursing. The perioperative basic conditions, such as the surgical time, the postoperative ambulation time, the hospital stay, the incidence of postoperative complications, and the psychological status evaluated by the connor-Davidson resilience scale (CD-RISC), the self-management ability evaluated by the exercise of self-care agency scale (ESCA) and the quality of life evaluated by the quality of life scale (QLQ-C30) before and after intervention of the patients were compared between the two groups. Results: There was no significant difference in the operation time and the postoperative ambulation time of the patients between the two groups (P>0.05). The hospitalization time (6.7±1.9d) and the incidence of the postoperative complications (20.8%) of the patients in the study group were significantly lower than those (7.8±2.0d and 38.5%) of the patients in the control group. The scores of CD-RISC scale, ESCA scale and QLQC30 scale of the patients in the two groups after intervention had increased significantly, and which (63.81±10.25 points, 110.97±14.66 points and 85.60±12.65 points) of the patients in the study group were significantly higher than those (56.39±11.31 points, 96.42±16.82 points and 77.91±13.84 points) of the patients in the control group (all P<0.05). Conclusion: The empowerment education under staged management model combined with the need hierarchy nursing for the patients with laparoscopic ovarian tumor excision during perioperative period can accelerate their postoperative recovery and improve their psychological resilience and self-management ability, and which is helpful to improve their quality of life.