Abstract To observe the effects of transcutaneous electrical stimulation (TENS) combined with intravenous dexmedetomidine used prior to anesthesia induction of patient with transvaginal hysterectomy combined with vaginal repair on their recovery after surgery. Methods: 100 patients who wanted transvaginal hysterectomy combined with vaginal repair were selected and were divided into two groups by the random number table method from October 2020 to December 2023. The patients in the control group were given intravenous dexmedetomidine prior to anesthesia induction, and the patients in the observation group were given the combined TENS combined with intravenous dexmedetomidine prior to anesthesia induction. The visual analog (VAS) scores at resting and cough, the exhaust time, the duration of hospital stay, the residual urine volume, the comfort (BCS) score, the pain stress factor level and the occurrence of adverse reactions of the patients were compared between the two groups. Results: The exhaust time of the patients in the observation group was significantly shorter than that of the patients in the control group, and there were no statistically significant differences in the residual urine volume and the duration of hospitalization of the patients between the two groups (P>0.05). The VAS scores at resting and cough of the patients in the observation group at 4h, 12h, 24h and 48h after surgery were significantly lower than those of the patients in the control group, and the BCS score of the patients in the observation group at 4h, 12h, 24h and 48h after surgery was significantly higher (P<0.05). There was no significant difference in the pain stress factor level before surgery of the patients between the
two groups (P>0.05). 24 hours after operation, The levels of cortisol (Cor), neuropeptide Y (NPY) and β-endophytin (β-EP) of the patients in the two groups after surgery had increased significantly (P<0.05), and which of the patients in the observation group at 24 hours after surgery were significantly lower than those of the patients in the control group (P<0.05). There were no significant differences in the incidences of nausea and vomiting, thirst, bradycardia, skin itching and other adverse reactions of the patients between the two groups. Conclusion: The TENS combined with intravenous dexmedetomidine used prior to anesthesia induction of the patient with transvaginal hysterectomy combined with vaginal repair can reduce the release of their pain factors, relieve their pain degree, improve their comfort and their postoperative recovery.
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