To investigate the fertility pressure of infertility patients with polycystic ovary syndrome(PCOS), and to study its correlation with the life quality and the coping style of the patients. Methods: 92 infertility patients with PCOS treated in the hospital from January 2021 to May 2023 were selected in this study. The fertility pressure evaluated by fertility pressure inventory(FPI), the quality of life evaluated by fertility quality of life questionnaire(FertiQol) and the coping style evaluated by trait coping style questionnaire(CSQ) of the patients were conducted, and their correlation among each other was studied. The influencing factors of the fertility pressure of the infertility patients with PCOS were analyzed. Results: The total scores of FPI and FertiQol questionnaire, and the scores of the positive and negative coping in CSQ questionnaire of 92 infertile patients with PCOS were 36.67±7.29 points, 89.37±11.48 points, 34.34±3.73 points and 33.27±4.62 points, respectively, and which indicated that the fertility stress and the quality of life of these patients were all at a medium level, and these patients tended to have the negative coping. The patients with the advanced age, the longer duration of the diagnosed infertility by PCOS, the lower family monthly income, the bad mood, or the worse conjugal relations had higher fertility stress score(P<0.05). The age ≥30 years old, the duration of the diagnosed infertility by PCOS >3 years, the family monthly income ≤3000 Yuan, the negative mood, the general or poor conjugal relations, the low quality of life and the negative coping style of the patients were the influencing factors of their fertility stress. The fertility stress score of the patients was positively correlated with their negative coping style score, and was negatively correlated with their quality of life score and positive coping style score(all P<0.05). Conclusion: The fertility pressure of the infertility patients with PCOS is affected by their age, duration of the diagnosed infertility by PCOS, family monthly income, bad mood or not and the conjugal relations. The fertility pressure of the patients is correlated with their quality of life and coping style.