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| Prediction effect of the prognostic nutrition index value for the acute radiation enteritis of patients with cervical cancer radiotherapy |
| Fuyang Cancer Hospital, Fuyang, Anhui Province, 236048 |
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Abstract To analyze the predictive effect Prediction effect of the prognostic nutrition index (PNI) value for the acute radiation enteritis of patients with cervical cancer and radiotherapy. Methods: The clinical data of 80 patients with cervical cancer admitted to the hospital from January 2020 to August 2023 were included in this study. According to the occurrence of the acute radiation enteritis after radiotherapy, these patients were divided into group A (patients with acute radiation enteritis) and group B (patients without acute radiation enteritis). The clinical data, such as the pathological classification, the clinical stage of cervical cancer and the PNI value of the patients were compared between the two groups. Logistic multivariate model was used to analyze the related factors affecting the occurrence of the acute radiation enteritis of the patients. Receiver operating characteristic (ROC) curve was used to analyze the efficacy of the PNI value of the patients for predicting the occurrence of their acute radiation enteritis. Results: Among 80 patients, there were 17 patients with acute radiation enteritis, with an incidence of 21.3%. The clinical symptoms of the patients were mainly the grade 1-2 diarrhea and the grade 1-2 abdominal pain. Logistic multivariate regression analysis showed that the body mass index (BMI) <18.5 kg/m2, the FIGO stage III-IV, the lymph node metastasis, the hemoglobin (Hb) <110 g/L, and the PNI value <48.84 of the patients were all the independent risk factors affecting the occurrence of their acute radiation enteritis (P<0.05). ROC curve showed that the area under the curve (AUC), the sensitivity and the specificity of the PNI value of the patients for predicting their acute radiation enteritis were 0.875, 88.3% and 87.3%, respectively. Conclusion: The PNI value of the patients with cervical cancer and radiotherapy can provide a reliable reference for predicting their acute radiation enteritis occurrence.
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