|
|
|
| Diagnostic value of the vaginal color Doppler ultrasound parameters values combined with the serum anti-Mullerian hormone level and the luteinizing hormone/follicle-stimulating hormone value of the women for their occurrence of polycystic ovary syndrome |
| 1.Nanjing Lishui District People's Hospital, Nanjing, Jiangsu Province, 211200；2.Cuhk Hospital Affiliated to Southeast University, Nanjing |
|
|
|
|
Abstract To detect the expression levels of anti-Mullerian hormone (AMH), and the value luteinizing hormone (LH)/follicle-stimulating hormone (FSH) in serum of women with polycystic ovary syndrome (PCOS), and to explore the diagnostic value of vaginal color Doppler ultrasound parameters values combined with serum AMH level and the LH/FSH value of the women for their PCOS. Methods: A total of 95 women with PCOS who visited the gynecological outpatient department from March 2019 to March 2022 were included in research group. Another 68 healthy women who underwent physical examination during the same period were included in control group. The serum AMH, LH, and FSH levels of the women in the two groups were detected. The ovarian volume, the follicle number, and the endometrial thickness of the women in the two groups were examined by vaginal color Doppler ultrasound. Pearson correlation analysis was used to analyze the correlation between the serum AMH level and the LH/FSH value of the women and their vaginal ultrasound parameters values. Multivariate logistic regression was used to analyze the influencing factors of PCOS occurrence, and receiver operating characteristic (ROC) curves was used to analyze the diagnostic efficacy of the combined vaginal color Doppler ultrasound combined with the serum AMH level and the LH/FSH value for PCOS. Results: The serum AMH level (9.56±2.75ng/ml) and the LH/FSH value (2.24±0.76) of the women in the research group were significantly higher than those (5.74±1.48ng/ml and 1.21±0.28) of the women in the control group. The ovarian volume and the number of follicles of the women in the research group were significantly higher than those of the women in the control group, and the endometrial thickness of the women in the research group were significantly less (all P＜0.05). In the research group, the serum AMH level and the LH/FSH value of the women were positively correlated with their ovarian volume and number of follicles, and were negatively correlated with their endometrial thickness (all P＜0.05). Multivariate logistic regression analysis showed that the increased AMH level, the LH/FSH value, the ovarian volume, the follicle number, and the decreased endometrial thickness of the women were all the factors influencing their PCOS occurrence (all P＜0.05). The diagnostic efficacy of the color Doppler ultrasound parameters values combined with the serum AMH level and the LH/FSH value of the women for their PCOS occurrence was significantly higher than that of the color Doppler ultrasound parameters values, the serum AMH level, or the LH/FSH value alone (P＜0.05). The area under the curve and the sensitivity of the color Doppler ultrasound parameters values combined with the serum AMH level and the LH/FSH value of the women for their PCOS occurrence were 0.962 and 95.7%. Conclusion: The serum AMH level and the LH/FSH value of the women with PCOS increase obviously. The vaginal color Doppler ultrasound parameters values combined with the serum AMH level and the LH/FSH value of the women for diagnosing their PCOS occurrence can improve the efficiency.
|
|
|
|
|
|
|
|
|
