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| Value of the decline of postoperative β-hCG level in the primary treatment of patients with cesarean scar pregnancy in their prognosis |
| 1. Women’s Hospital School of Medicine School of Zhejiang University, Hangzhou, Zhejiang Province, 310006; 2. Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan |
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Abstract To explore the value of the decline of postoperative βhuman chorionic gonadotropin (hCG) level in the primary treatment of patients with cesarean scar pregnancy (CSP) in their prognosis. Methods: The clinical data of the patients with CSP from January 2009 to September 2019 in Women’s Hospital School of Medicine Zhejiang University, were analyzed retrospectively. Among them, 66 patients who failed in primary treatment and needed to be treated again were included in study group. And 1: 4 match was used to seen 258 patients who had been treated successfully and did not need to be treated again in the control group during this period. The decline percentage rate of the β-hCG level after surgery of the patients were compared between the two groups. Results: There were significant difference in the decline percentage rate of the postoperativeβ-hCG level (60.3±14.2% vs. 67.9±13.2%) of the patients between the two groups (Z=3.28 and 3.90, P<0.05). Receiver operator characteristic (ROC) curve analysis showed that the optimum critical value, the sensitivity, and the specificity of the decline percentage rate of the postoperativeβ-hCG level of the patients for diagnosing their treatment failure were 66.6%, 68.2%, and 57.8%, respectively. Conclusion: The decline percentage rate of the postoperativeβ-hCG level of the patients is <66.6%, which suggests that the remedial treatment again should be conducted in these patients.
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