To analyze the influence of different seriousness of gestational thrombocytopenia (GT) of pregnant women on their coagulation function, delivery mode, and neonatal outcomes. Methods: The clinical data of 120 pregnant women with GT were selected in this study. The women were divided into group A (35 cases with platelet count≤20×109/L), group B (42 cases with 20×109/L< platelet count <50×109/L), and group C (43 cases with 50×109/L≤ platelet count <100×109/L) according to their PLT level. 45 healthy pregnant women were selected in control group during the same period. The coagulation function index level, delivery mode, and neonatal outcomes of the women were compared among the four groups. Results: The platelet count of the women in group A, group B, and group C had increased gradually, and which was significantly lower than that of the women in the control group. The mean platelet volume (MPV) and platelet distribution width (PDW) of the women in group A, group B, and group C had decreased gradually, and which were all significantly higher than those of the women in the control group (P＜0.05). There were no significant differences in the clotting indexes, such as prothrombin time (PT), thrombin time (TT), activated partial thrombin time (APTT), and fibrinogen (FIB), of the women among the four groups (P＞0.05). The rate of cesarean section of the women in group A (62.9%), group B (45.2%), and group C (34.9%) had decreased gradually, and which was significantly higher than that (26.7%) of the women in the control group. The incidence of postpartum hemorrhage of the women in group A (34.3%), group B (14.3%), and group C (7.0%) had decreased gradually, and which was significantly higher than that (2.2%) of the women in the control group (P＜0.05), there were no significant differences in the birth weight and the incidence of neonatal asphyxia among the four groups (P＞0.05). The preterm birth rate and the incidence of neonatal thrombocytopenia of the women in group A (45.7% and 51.4%), in group B (21.4% and 28.6%), and in group C (18.6% and 16.3%) were significantly higher than those (4.4% and 4.4%) of the women in the control group (P＜0.05). Conclusion: The levels of PLT, MPV, and PDW of the pregnant women with different seriousness of GT are obviously abnormal, but which have less influence on the coagulation function of the women. The more seriousness of GT of the pregnant women, the more likely to increase their adverse outcomes, such as cesarean section, postpartum hemorrhage, premature delivery, neonatal thrombocytopenia, etc. The management of the pregnant women with GT should be strengthened to reduce the risk of their adverse pregnancy outcomes in clinic.