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| Correlation between the levels of prolactin and 25 hydroxyvitamin D of women and their multiple hysteromyoma |
| Anhui Wannan Rehabilitation hospital, The Fifth People's Hospital of Wuhu, Anhui Province, 241000 |
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Abstract To explore the correlation between the levels of prolactin (PRL)and 25 hydroxyvitamin D ［25-（OH）-D］ of women and their multiple hysteromyoma. Methods: 98 women with multiple hysteromyoma who wanted surgery were selected in study group and 50 healthy women were selected in control group from March 2018 to January 2022. The levels of serum PRL and 25-(OH)-D of the women were compared between the two groups. The correlation between the values of the diameter and the volume of different hysteromyoma, and the levels of ER and PR expression of the women in the study group and their levels of PRL and 25-(OH)-D was analyzed. Results: The PRL level (41.17±6.39ng/ml)of the women in the study group was significantly higher than that (15.23±4.82ng/ml)of the women in the control group. The level of 25-(OH)-D (22.51±6.27ng/ml)of the women in the study group was significantly lower than that (58.64±6.65ng/ml)of the women in the control group (all P＜0.05). The PRL level and the 25-(OH)-D level of the women with multiple hysteromyoma were positively correlated with their hysteromyoma diameter and volume, and their ER and PR expression levels (all P＜0.05). Conclusion: The levels of PRL and 25-(OH)-D of the women with multiple hysteromyoma are significant different from those of the healthy women. The levels of PRL and 25-(OH)-D of the women with multiple hysteromyoma are all positively correlated with their hysteromyoma diameter and volume, and their ER and PR expression levels, and which may potentially assist in the diagnosis of multiple hysteromyoma of the women.
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