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Abstract Gestational diabetes mellitus (GDM) of the women is the abnormality of glucose tolerance that first occurrence or discovery during pregnancy, and has serious adverse effects on the mother, the fetus, and the baby, and which as the most common pregnancy complication has been become one of the current research hotspots. The oral glucose tolerance tests (OGTT) in China are mainly performed during 24-26 gestational weeks, but at this time, the time window left for clinical treatment is already very short, and the screening process is tedious, and time-consuming and labor-intensive, with poor compliance of these pregnant women. At present, the extensive researches have been achieved on the early predictors of GDM. This article focuses on the metabolic indicators for predicting GDM during the first trimester of pregnancy.
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