To investigate the correlation of the expression levels of Th1/Th2 related cytokines of women with cervical cancer and their pathological characteristics and prognosis. Methods: The clinical data of 82 patients with cervical cancer (in study group) who had treated in hospital from January 2020 to January 2021 were collected. 68 healthy women who had received physical examination in hospital were selected in control group during the same period. The morning fasting elbow venous blood of the women in the two groups was collected for detect the levels of their Th1/Th2 related cytokines. The levels of the Th1/Th2 related cytokines were compared among of the women with different differentiation degrees, among of the women with different clinical stages, and among of the women with different prognostic outcomes in the study group. The correlation between the levels of Th1/Th2 related cytokines of the women with cervical cancer and their prognosis was analyzed by Spearman correlation coefficient analysis. Results: The levels of serum interferon-γ (IFN-γ, 33.24±7.25), interleukin (IL) -2 (24.17±6.22), IL-4 (25.38±5.92), and IL-6 (30.83±8.02pg/ml) of the women in the study group had significantly different from those (51.29±8.76 pg/ml, 37.45±8.03 pg/ml, 13.32±3.41 pg/ml, and 20.82±5.47 pg/ml) of the women in the control group (all P＜0.05). With the increase of differentiation degree and clinical stage of cervical cancer of the women in the study group, the abnormal levels of serum IFN-γ, IL -2, IL-4, and IL-6 of the women had aggravated. In the study group， the levels of serum IFN-γ, IL -2, IL-4, and IL-6 of the women with death were significantly higher than those of the survival womeduring 1-year of follow-up, and which were positively correlated with the poor prognosis of these women (all P＜0.05). Conclusion: The level of serum Th1/Th2 related cytokines of the women with cervical cancer is abnormal, and which is positively correlated with the poor prognosis of these women. In order to improve the prognosis of the women with cervical cancer, early diagnosis and treatment can be carried out in these women by monitoring their level of Th1/Th2 related cytokines.