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| Value of the combined detections of peripheral blood hemoglobin, platelet count, plasma fibrinogen, and D dimer of advanced puerperae for predicting their postpartum hemorrhage |
| Lingao County People's Hospital, Hainan Province, 571800 |
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Abstract To explore the value of the combined detections of peripheral blood hemoglobin (Hb), platelet count (PLT), plasma fibrinogen (FIB), and D dimer (D-D) of advanced puerperae for predicting their postpartum hemorrhage (PPH). Methods: The clinical data of 114 advanced puerperae who wanted delivery in the hospital were collected between January 2021 and January 2022. Among these puerperae, there were 50 cases with normal delivery in control group and 64 cases with PPH in study group. According to the blood loss, the puerperae in the study group were divided into group A (44 cases with common PPH) and group B (20 cases with severe PPH). The levels of Hb, PLT, FIB, and D-D of the puerperae were compared among these groups. The correlation between the levels of Hb, PLT, FIB, and D-D of the puerperae and their blood loss was analyzed. The predictive value of the levels of Hb, PLT, FIB, and D-D of the puerperae for their PPH was also analyzed. Results: The PLT and FIB levels of the puerperae in the control group were significantly higher than those of the puerperae in the study group, and the D-D level and the bleed loss of the puerperae in the control group were significantly less (P＜0.05), but the Hb level of the puerperae had no significant differences between the two groups (P>0.05). The PLT and FIB levels of the puerperae in group A were significantly higher than those of the puerperae in group B, the D-D level of the puerperae in group A was significantly lower than that of the puerperae in group B (P 0.05), but the Hb level of the puerperae had no significant difference between the two groups (P>0.05). The analysis of receiver operating characteristic curve showed that, the area under the curve of the combined levels of Hb, PLT, FIB, and D-D of the puerperae for predicting their PPH was 0.856, which was significantly higher than that (0.511, 0.738, 0.612, or 0.796) of the Hb level, PLT level, FIB level, or D-D level alone. The levels of the peripheral blood PLT and FIB of the puerperae was negatively correlated with their blood loss, the D-D level of the puerperae was positively correlated with their bleeding loss (all P<0.05), but the Hb level of the puerperae was no correlation with their bleeding loss (P>0.05). Conclusion: The antenatal combined detections of Hb, PLT, FIB, and D-D of the advanced puerperae for predicting their PPH has some clinical significances.
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